Portrayal of Asthma Trajectories

Asthma is a heterogeneous disease with clinical manifestations that typically vary with the stage of life. Asthma, eczema, and rhinitis often co-occur, and can be classified as allergic comorbidities. Asthma, eczema, and rhinitis are complex diseases, with genetic and environmental factors interlinked through both IgE-associated and non–IgE-associated mechanisms. The development of asthma is a dynamic process. For some patients, asthma starts early, whereas it debuts later in life for others. The disease may progress, remit, or relapse over time.6 The goal of asthma treatment is to achieve and maintain asthma control and minimize exacerbations and lung function loss. Most patients with asthma have mild or moderate disease, but 1 group has poor outcomes across the spectrum of disease severity. Asthma has many underlying biological pathways that lead to different disease trajectories. Investigating asthma trajectories provides a foundation for gaining increased knowledge on asthma development and associated markers, and disease outcomes can thereby be improved.

Investigating well-being and health in adolescents is important, knowing that these aspects strengthen essential developmental tasks, including maturation of emotional and cognitive abilities to become independent, completion of education, and transition to employment, civic engagement, and establishment of lifelong relationships. Adolescence is a key developmental time period marked by rapid neurocognitive and social developmental changes, as well as the first emergence of mental health disorders. In general, previously published studies reported that youth with asthma perceived a lower general health compared with their peers without asthma. Asthma severity and medication use are seen as predictors of mental being in patients with asthma. Moreover, adolescence could influence the course of asthma, and overall well-being. Therefore, repeated measurements within the same individual during adolescence, and also testing for interaction effects of “asthma and age” and “asthma and gender” will give more robust results than using only one measurement at one time point.

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Media Contact:   

Alina Grace            

Journal Manager

Asian Journal of Biomedical & Pharmaceutical Sciences

Email: jbiopharm@scholarlypub.com